Targeting Zombie Cells to Treat Dementia

Wednesday, April 17, 2024, 3:00PM
No charge for Four Arts members

with Dr. Miranda Orr

Dr. Miranda E. Orr, Ph.D., an Assistant Professor of Gerontology and Geriatric Medicine at Wake Forest University School of Medicine, will discuss her cutting-edge research targeting senescent “zombie” cells to treat Alzheimer’s disease, recently featured in National Geographic. These cells develop mechanisms to avoid the natural death cycle that come to all cells and live on, accumulating in the brain, causing brain inflammation, and releasing damaging toxins. Dr. Orr’s work is now in a phase 2 clinical trial with support from the Alzheimer’s Drug Discovery Foundation.

Presented by The Alzheimer’s Drug Discovery Foundation in partnership with Heidi and Tom McWilliams

Alzheimer’s Disease affects more than 50 million people and is the only top 10 cause of death that cannot yet be “prevented, treated or cured.” “Tomorrow’s Breakthroughs Today” features world-class scientists discussing the path toward new, cutting-edge treatments for Alzheimer’s and other dementias. This series invites three top investigators to share the latest updates on their research with moderator Dr. Howard Fillit, Co-Founder and Chief Science Officer of the Alzheimer’s Drug Discovery Foundation (ADDF). Founded in 1998 by Leonard A. and Ronald S. Lauder, the ADDF is dedicated to developing therapeutics and biomarkers that prevent, treat, and cure Alzheimer’s and related dementias.